ABSTRACT
INTRODUCTION: Haemovigilance is defined as a set of surveillance procedures covering whole transfusion chain from the collection of blood and its components to the follow up of its recipients, intended to collect and access information on unexpected or undesirable effects resulting from the therapeutic use of labile blood products, and to prevent their occurrence and recurrence.(1) AIMS AND OBJECTIVES: An effective effort towards the study of haemovigilance programme by evaluating the different adverse reactions occurring due to blood transfusion in patient receiving regular or temporary blood transfusion.The ultimate goal of a haemovigilance system is to improve the safety of blood transfusion. METHODS & MATERIALS: The current study was done at Blood bank AMC MET Medical College & LG Hospital, Ahmedabad. All the adverse reactions related to transfusion of blood components between April-2014 to March-2016 issued were studied.RESULT: In this study, total 17264 blood component (PCV, PRC, FFP, CRYO) were issued. From total 20 BTR, 18 BTR due to PCV, and 02 BTR due to PRC. In which 08 patients have febrile reaction, 07 patients have allergic reaction, 02 patients have non TRALI associated dyspnea and 01 patient has uneasiness-giddiness due to the PCV. 02 patients have allergic reaction which occurred due to PRC.CONCLUSION: Haemovigilance is an essential component of quality management in a blood system and is needed for the continual enhancement of quality and safety of blood products and transfusion process by monitoring and safeguarding the adverse events associated with the use of blood products.
ABSTRACT
INTRODUCTION:Benign proliferative breast lesions deserve attention because of high prevalence and impacton women’s life and due to cancerous potential of some histological types.AIMS AND OBJECTIVES:i) To establish the significance of histopathology in the diagnosis of benign proliferative breast lesions.ii) To ascertain the relative frequency of each type of lesion in different age groups and its significance.iii) To compare the study with other different study. MATERIAL AND METHOD:Total 3077 biopsy was received in histopathology department of our institution during August 2015 to July 2016. Among these, 120 cases were of breast lesions. RESULT:Out of 120 breast lesions, 97 were of benign lesions and 23 were of malignant lesion in different age groups. Among these 97 benign proliferative breast lesions, 46 cases (42.22%) has fibroadenoma , 8 cases (8.24%) has epithelial hyperplasia, 27 cases (27.83%) has fibrocystic disease of breast ,5 cases (5.15%) has gynecomastia, 6 cases (6.18%) has phylloid tumour, 2 cases (2.06%) has intraductal papilloma and 3 cases (3.09 %) has adenoma.CONCLUSION:Based on morphological distribution, fibroadenoma constitute maximum number of cases followed by fibrocystic disease of breast. Phylloid tumor is rare but it has clinical relevance. Fibroadenoma is more common in younger age group (16-30 years) whereas fibrocystic disease of breast is more common in older age group (31-45 years).